brown, grey, gray, dead, head, grey, greenUNLOCK: Unlock this item by beating Challenge #14 (It's in the Cards). * boss rush pool, boss rush room, shop room pool, shop item pool, item room, treasure room,
your tear damage + 20 to any enemies which come into contact with them.• The beams now have improved targetting and will attempt to spawn on top of enemies where possible. • When used, rerolls each item you currently own into another
items, giving you a new item to over-ride each of the one you had.• A reference to the infamous 'Missingno' glitch from Pokemon.UNLOCK: Unlock this item by beating Boss Rush with Lazarus.
grey, gray, feet
*astrology, astronomy, item room, treasure room, item room pool, nys, notyoursagittarius, * item room, treasure room, item room pool, gold, ingot, bar, orange• All future pennies, keys, bombs and hearts will drop in pairs.• Does not work for soul hearts, nickels, dimes, cards or pills.
* item room, treasure room, item room pool, pink, blue, grey, gray• A spacebar item that fires 8 of Isaac's tears in a circle around him.UNLOCK: Unlock this item by beating the Isaac boss with Isaac. pill if no other pills were used yet.
with enemies and the beams deal damage equal to your tear damage + 20.• Tears are now white, do a lot more damage and move slower across the screen with a homing effect.
your items into heart containers.UNLOCK: Unlock this item by blowing up 30 slot machines. * item room, treasure room, item room pool, silver, gray, grey, red, machine* item room, treasure room, item room pool, green, black• +2 Damage Up for tears fired from Isaac's left eye.• If you have an item which modifies which eye you fire tears from, each shot has a 50% chance to do +2 Damage. Head, Tiny Planet, Inner Eye (Triple Shot), Mutant Spider (Quad Shot) * boss room pool, boss room item, the lost item pool, plasters, white• Everytime a bomb explodes, it will release a circle of tears outwards, much like the Tammy's Head effect.• The tears from each bomb are affected by any tear modifiers Isaac has on his own tears.• The tears caused by Sad Bombs are much larger and do a lot more damage than Isaac's normal tears. • Gives the player an invulnerability effect which lasts for a few seconds. * secret room pool, mondrian, painting, yellow, blue, red, white• Tears now have a chance to apply the fear effect to enemies, which causes them to run away from Isaac.• The chance to fear enemies is affected by your luck stat and at +20 Luck it will activate every time.• An item only found in the devil room pool (Note: The Fallen boss pulls items from the Devil Room Pool)* devil pool, devil room pool, devil deal, grey, gray, fist, glow• Immunity to all floor curses (e.g. grey, gray multipliers)• This item can only be found in the item room pool, unlike the original game where it was also a god item* item room, treasure room, item room pool, crown, thorns, brown, hat• A familiar which follows Isaac and shoots normal tears which do 3.5 damage.• Brother Bobby fires tears at a rate of 1 tear per second. * secret room pool, , the lost item pool, purple, black, grey, gray, flower• When you take damage, 1 or 2 coins will drop on the floor.• When playing as the Keeper, this item drops 0-1 coins instead. coin, bomb, key)* normal beggar pool, normal judgement pool, coin * devil pool, devil room pool, devil deal, grey, gray, bloody• Spawns a trapdoor at Isaac's feet which allows him to travel to the next floor.• The trapdoor has a 10% chance to become a Black Market.• Has no effect in Sheol, Cathedral, Chest and Dark Room.• Cannot spawn a trapdoor directly infront of a secret room entrance.• Can destroy rocks if used when Isaac is flying over a rock.
* item room, treasure room, item room pool, DIO, dice pip, orange, brown, turban• When used, copies the effect of the tarot card you are currently holding without consuming it.• The Blank Card can also be used to mimic mystic runes as well as tarot cards.UNLOCK: Unlock this item by beating the Isaac boss with Eden. Can be used with Placebo to generate infinite batteries• Amnesia - Hides the floor map for the rest of the current floor (same as curse of the lost).
Proptosis, Number One, Mom's Contacts or Dark Matter.
If you get hit while Cursed eye is a solid black colour you are guaranteed to be teleported to another random room on the floor.
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