Masterson, Joseph E. McGann, Virginia G. and PETZOLDT, KLAUS What part of the immune system is important to infection with Francisella Tularensis: CMI- Macrophage activation is CRUCIAL for resolution Roche, Marly I. Johansson, T. Wren, Brendan W Eigelsbach, Henry T.

Tularemia is caused by the bacterium Francisella tularensis (F. tularensis), one of the most infectious agents known.Not only does F. tularensis infect a very high number of different species (greater than 250), an extremely low number of organisms (less than 10) are capable of establishing a potentially lethal infection.. Sharon, Jacqueline Francisella tularensis is a highly infectious agent but its virulence factors have not been well characterized.

1987.

Forsman, Mats Haithcoat, Judith Chu, May C Prior, Joann

2018 Jun 15;8:182. doi: 10.3389/fcimb.2018.00182. Lindler, Luther E and and

Svensson, Kerstin (14) Cell structure and metabolism Most of the Francisella bacteria are homogeneous in shape and size.

1989. Williams, J.C. eCollection 2018.Bandara AB, Champion AE, Wang X, Berg G, Apicella MA, McLendon M, Azadi P, Snyder DS, Inzana TJ.PLoS One. 2006.

F tularensis is considered a category A bioterrorism agent (CDC: Select agents and toxins).The following information supports the use of F tularensis as a potential biological weapon (CDC: Key facts about tularemia, Christopher 1997, Dennis 2001). F tularensis is highly infectious, occurs widely in nature, and can be isolated and grown in quantity in the laboratory. Apicella, Michael A.

At least two such virulence factors …

Andersson, Siv G E

Sandström, Gunnar

SUMMARY Francisella tularensis is the etiological agent of tularemia, a serious and occasionally fatal disease of humans and animals. Observations on the infection of chick embryos with Fatty acid composition of bacterial membrane and wall lipidsAirborne micro-organisms: a technique for studying their survivalThe development of resistance in mice immunized with soluble antigen derived fromThe Collison nebulizer: description, performance and applicationStudies on Tularaemia.

As low as 10 colony-forming unit (CFU) of F. tularensis ssp. Find out more about sending to your Kindle. Andersson, Siv G E

Capsules were also removed by suspension of F. tularensis in hypertonic sodium chloride. Ohara, Yoshiro

Email your librarian or administrator to recommend adding this journal to your organisation's collection.Email your librarian or administrator to recommend adding this journal to your organisation's collection.Full text views reflects the number of PDF downloads, PDFs sent to Google Drive, Dropbox and Kindle and HTML full text views.Abstract views reflect the number of visits to the article landing page. Ben Nasr, Abdelhakim

This study screened a total of 3,936 transposon mutants of the live vaccine strain for infection in a mouse model of respiratory tularemia by signature-tagged mutagenesis. eCollection 2015.Ann N Y Acad Sci. Gunn, John S. McGann, Virginia G. 2008.

Sato, Tadashi Clay, Corey D. McLendon, Molly K. Johansson, Daniel Titball, Richard W

Larsson, Eva 2006. 2006. Francisella tularensis is a gram-negative pathogen that causes life-threatening infections in humans and has potential for use as a biological weapon. and Masterson, Joseph E. Duffield, Melanie

HENSEL, ANDREAS Sjöstedt, A. Sandström, G. The genetic basis of the F. tularensis virulence is poorly understood.

Johansson, Daniel

Champion AE, Bandara AB, Mohapatra N, Fulton KM, Twine SM, Inzana TJ.Front Cell Infect Microbiol. and 2007. and and Tärnvik, A. Löfgren, S. doi: 10.1371/journal.pone.0011060.Front Cell Infect Microbiol. It is able to infect a variety of animals and insects and can persist in the environment, thus Francisella spp. Regardless of the method, scientists know that the genes for this process are encoded in the Francisella pathogenicity island (FPI), which codes for a bunch of virulence factors. 2005. Larsson, Pär **Virulence factors of Francisella Tularensis (2): *Polysaccharide capsule (protects from complement > strongly associated with pathogencicity)* LPS. Duffield, Melanie Oyston, Petra C F

Gunn, John S. Wagg, Jonathan K

Sjöstedt, Anders Sjöstedt, Anders

1981.

Sato, Tadashi Sandström, G.